| Bioactivity | Fabomotizole hydrochloride (CM346 hydrochloride) is an anxiolytic drug. Fabomotizole hydrochloride produces anxiolytic and neuroprotective effects without any muscle relaxant actions. |
| Invitro | Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA. |
| Name | Fabomotizole hydrochloride |
| CAS | 173352-39-1 |
| Formula | C15H22ClN3O2S |
| Molar Mass | 343.87 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Afobazole, From Wikipedia |
Fabomotizole hydrochloride
CAS: 173352-39-1 F: C15H22ClN3O2S W: 343.87
Fabomotizole hydrochloride (CM346 hydrochloride) is an anxiolytic drug.Fabomotizole hydrochlorideproduces anxiolytic and
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