PeptideDB

Fabimycin

CAS: 2651965-71-6 F: C23H25ClN4O3 W: 440.92

Fabimycin is a FabI inhibitor with potent antibacterial activity against gram-negative bacteria. Fabimycin is effective
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Fabimycin is a FabI inhibitor with potent antibacterial activity against gram-negative bacteria. Fabimycin is effective against drug-resistant gram-negative Infections in vivo[1].
Invitro Fabimycin shows outstanding activity against S. aureus (MIC: 4 ng/mL), E. coli MG1655 (MIC: 2 μg/mL)[1].Fabimycin (4 μg/mL) inhibits 90% of the strainsagainst a panel of 100 K. pneumoniae clinical isolates[1].Fabimycin enhances the stability of the enzyme-inhibitor complex significantly more than the less active enantiomer in both E. coli and A. baumannii versions of FabI[1].
Name Fabimycin
CAS 2651965-71-6
Formula C23H25ClN4O3
Molar Mass 440.92
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.