Bioactivity | FabH-IN-1 (compound 3f) is an inhibitor of bacterial 3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme which is a broad-spectrum antimicrobial target. FabH-IN-1 is effective against gram-positive and gram-negative. FabH-IN-1 is also a good antioxidant[1]. |
Target | 3-oxoacyl- synthase 3 (FabH) enzyme |
Name | FabH-IN-1 |
CAS | 2692652-49-4 |
Formula | C17H16N2OS |
Molar Mass | 296.39 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Ahmad H, et, al. A combine approach of chemical synthesis, biological evaluation and structural dynamics studies revealed thiazole substituted arylamine derivatives as potent FabH enzyme inhibitors. Bioorg Chem. 2020 Dec;105:104426. |