| Bioactivity | FXR agonist 9 (compound 26) is an oral active and selectivity FXR partial agonist with the EC50 of 0.09 µM (75.13 % maximum efficacy). FXR agonist 9 ameliorates pathological features in HFD + CCl4-(HY-Y0298) induced metabolic dysfunction-associated steatohepatitis mice[1]. |
| CAS | 2982502-32-7 |
| Formula | C28H30N2O5 |
| Molar Mass | 474.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen C, et al. Design, synthesis and FXR partial agonistic activity of anthranilic acid derivatives bearing aryloxy moiety as therapeutic agents for metabolic dysfunction-associated steatohepatitis. Bioorg Chem. Published online November 3, 2024. |
FXR agonist 9
CAS: 2982502-32-7 F: C28H30N2O5 W: 474.55
FXR agonist 9 (compound 26) is an oral active and selectivity FXR partial agonist with the EC50 of 0.09 µM (75.13 % max
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.