| Bioactivity | XIIa-IN-1-IN-2 (Compound 21) is a Factor XIIa inhibitor (Kiapp: 62.2 nM). XIIa-IN-1-IN-2 can be used for research of thrombosis[1]. |
| Target | Kiapp: 62.2 nM (Factor XIIa) |
| Name | FXIIa-IN-2 |
| Formula | C23H18N2O6 |
| Molar Mass | 418.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Davoine C, et al. Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy. Eur J Med Chem. 2023 Jul 16;259:115636. |