| Bioactivity | XIIa-IN-1-IN-3 (Compound 22) is a Factor XIIa inhibitor (Kiapp: 97.8 nM). XIIa-IN-1-IN-3 can be used for research of thrombosis[1]. |
| Target | Kiapp: 97.8 nM (Factor XIIa) |
| Name | FXIIa-IN-1 |
| Formula | C21H16N2O6 |
| Molar Mass | 392.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Davoine C, et al. Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy. Eur J Med Chem. 2023 Jul 16;259:115636. |