Bioactivity | FX-909 is a covalent peroxisome proliferator-activated receptor gamma (PPARG) inverse agonist. FX-909 can be used for the research of cancer[1]. |
In Vivo | FX-909 (0.03-1 mg/kg; BID for 21 days) 在 UMUC9 UC 异种移植小鼠模型中显示出抗癌作用[1]。 |
Name | FX-909 |
Formula | C17H10F2N2O3S |
Molar Mass | 360.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mertz J A, et al. Development of a surrogate tissue pharmacodynamic (PD) assay for clinical use with FX-909, a novel inhibitor of the urothelial luminal lineage transcription factor peroxisome proliferator-activated receptor gamma (PPARG). Cancer Research, 2023, 83(7_Supplement): 2802-2802. |