| Bioactivity | FV-100 is a potent, selective and orally active anti-varicella zoster virus agent. FV-100 is a prodrug of CF-1743. FV-100 exhibits very low toxicity in vivo[1][2]. |
| Invitro | FV-100 is intensely fluorescent when illuminated by wavelengths of 340-380 nm[1].FV-100 (1 h) produces a different distribution in HeLa cells[1]. |
| In Vivo | FV-100 (50-500 mg/kg; p.o.) does not induce biologically relevant respiratory changes or any apparent neuropharmacological effects in rats[2]. |
| Name | FV-100 |
| CAS | 956483-03-7 |
| Formula | C27H36ClN3O6 |
| Molar Mass | 534.04 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Migliore M, et, al. FV-100: the most potent and selective anti-varicella zoster virus agent reported to date. Antivir Chem Chemother. 2010 Jan 5;20(3):107-15. [2]. Pentikis HS, et, al. Pharmacokinetics and safety of FV-100, a novel oral anti-herpes zoster nucleoside analogue, administered in single and multiple doses to healthy young adult and elderly adult volunteers. Antimicrob Agents Chemother. 2011 Jun;55(6):284 |