| Bioactivity | FTY720-C2 is a derivative of FTY72 (HY-12005). FTY720-C2 promotes the expression of brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) in multiple system atrophy (MSA) models, without causing immunosuppression. FTY720-C2 improves motor dysfunction and reduces the levels of insoluble alpha-synuclein (aSyn) in MSA mouse models. FTY720-C2 is blood-brain barrier penetrate[1]. |
| CAS | 249289-10-9 |
| Formula | C21H35NO3 |
| Molar Mass | 349.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Segura-Ulate I. Therapeautic effects of FTY720 compounds in cellular and animal models of multiple system atrophy[D]. , 2018. |