| Bioactivity | FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC50 of <1 μM. FTO-IN-1 can be used for the research of cancer[1]. |
| Target | IC50: <1 μM (FTO) |
| Invitro | FTO-IN-1 (50 μM) inhibits FTO enzyme activity by 62% in vitro[1].FTO-IN-1 (50 μM) inhibits the viability of SCLC-21H, RH30 and KP3 cells, with IC50s of 2.1 μM, 5.3 μM, and 5.6 μM, respectively[1]. |
| Name | FTO-IN-1 |
| CAS | 2243944-92-3 |
| Formula | C18H16Cl2N4O2 |
| Molar Mass | 391.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang C, et, al. 2-(substituted benzene matrix) aromatic formate fto inhibitor, preparation method therefor, and applications thereof. WO2018157843A1. |
FTO-IN-1
CAS: 2243944-92-3 F: C18H16Cl2N4O2 W: 391.25
FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32,
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This product is for research use only, not for human use. We do not sell to patients.