| Bioactivity | FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis[1]. | ||||||||||||
| In Vivo | FT011 (100 mg/kg b.i.d., p.o., for 4 weeks) improves the cardiac function and and myocardial remodeling in myocardial infarction rats[1]. Animal Model: | ||||||||||||
| Name | FT011 | ||||||||||||
| CAS | 1001288-58-9 | ||||||||||||
| Formula | C20H17NO5 | ||||||||||||
| Molar Mass | 351.35 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Zhang Y, et al. A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction. Int J Cardiol. 2013 Sep 30;168(2):1174-85. |