| Bioactivity | FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM[1]. |
| Invitro | FR221647 对人腺苷脱氨酶 (ADA) 具有抑制作用，Ki 值为5.9 μM[1]。FR221647 在 100 μM 浓度下无细胞毒性[1]。 |
| Name | FR221647 |
| CAS | 256461-28-6 |
| Formula | C14H17N3O2 |
| Molar Mass | 259.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Terasaka T, et al. Structure-based de novo design of non-nucleoside adenosine deaminase inhibitors. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1115-8. |