| Bioactivity | FR181157, an orally active PGI2 agonist activity with especially good pharmacokinetic properties[1]. |
| Invitro | FR181157 exhibits high binding affinity for the IP receptor with a Ki of 54 nM and anti-aggregative potency with an IC50 of 60 nM[1]. |
| Name | FR181157 |
| CAS | 171046-15-4 |
| Formula | C30H26NNaO4 |
| Molar Mass | 487.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kouji Hattori , et al. A simple stereoselective synthesis and biological evaluation of FR181157: orally active prostacyclin mimetic. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4277-9. |