| Bioactivity | FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester series compound that can inhibit the contraction of the detrusor muscle of guinea pig bladder (IC50=3.3 μg/mL). After intravenous injection of FR 75513 into anesthetized rats, it also showed strong inhibitory activity on the detrusor contraction (ID50=0.04 mg/kg). |
| CAS | 127975-78-4 |
| Formula | C19H19NO7 |
| Molar Mass | 373.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Agents for the Treatment of Overactive Detrusor. I. Synthesis and Structure-Activity Relationships of 1, 1'-Biphenyl Derivatives |