Bioactivity | FR-181877 (compound 4) is an orally available non-prostaglandin PGI2 agonist. FR-181877 inhibits ADP (HY-W010918)-induced human platelet aggregation with an IC50 value of 0.081 μM[1]. |
CAS | 172936-99-1 |
Formula | C30H28N2O4 |
Molar Mass | 480.55 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tsubaki K, et al. A novel pyridazinone derivative as a nonprostanoid PGI2 agonist[J]. Bioorganic & medicinal chemistry letters, 2000, 10(24): 2787-2790. |