| Bioactivity | FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC50s of 0.51 μM (Ki=0.31 μM) and 0.33 μM (Ki=0.14 μM), respectively[1]. | ||||||||||||
| Invitro | In AP-1-transfected cells, FR180204 dose-dependently inhibits AP-1 transactivation with IC50 of 3.1 μM[1]. FR 180204 inhibits spontaneous mesothelioma cell growth[3]. | ||||||||||||
| Name | FR 180204 | ||||||||||||
| CAS | 865362-74-9 | ||||||||||||
| Formula | C18H13N7 | ||||||||||||
| Molar Mass | 327.34 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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