| Bioactivity | FOXM1-IN-1 is a potent FOXM1 inhibitor with an IC50 value of 2.65 µM. FOXM1-IN-1 shows antiproliferative activity. FOXM1-IN-1 decreases the the expression of FOXM1, PLK1, CDC25B protein[1]. |
| Target | IC50: 2.65 µM (FOXM1) |
| Invitro | FOXM1-IN-1 (0-10 μg/mL; 24 h) 降低SKOV3细胞中 FOXM1、PLK1、CDC25B蛋白的表达[1]。 Cell Proliferation Assay[1] Cell Line: |
| Name | FOXM1-IN-1 |
| Formula | C23H30ClNO3 |
| Molar Mass | 403.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gao Y, et al. Synthesis and antineoplastic activity of ethylene glycol phenyl aminoethyl ether derivatives as FOXM1 inhibitors. Eur J Med Chem. 2022 Dec 15;244:114877. |