| Bioactivity | FITC-β-Ala-Amyloid β-Protein (1-42) ammonium is a FITC tagged Aβ1-42 monomer peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease[1]. |
| Invitro | NNC 26-910 在 LPS 诱导的激活过程中减少亚硝化应激和小胶质细胞损伤,并在非炎症条件下增强 FITC-β-Ala-Amyloid β-Protein (1-42) ammonium (100 nM) 的吞噬作用[1]。 |
| Name | FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) |
| Shortening | {FITC-b-Ala}-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA (ammonium) |
| Formula | C227H330N58O66S2 |
| Molar Mass | 4991.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Joseph Schober, et al. NNC 26-9100 increases Aβ1-42 phagocytosis, inhibits nitric oxide production and decreases calcium in BV2 microglia cells. PLoS One. 2021 Jul 8;16(7):e0254242. |