Bioactivity | FINDY is a folding intermediate-selective inhibitor of DYRK1A. FINDY can inhibit Ser97 autophosphorylation with an IC50 value of 35 μM. FINDY can be used for the research of neurological disorder[1]. |
Target | IC50: 35 μM (Ser97 autophosphorylation) |
Invitro | FINDY (Compound 1) 抑制 Ser97 自磷酸化,IC50 值为 35 μM[1]。 |
Name | FINDY |
CAS | 1507367-37-4 |
Formula | C16H17NO2S2Si |
Molar Mass | 347.53 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yuka Miyazaki, et al. Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A. Eur J Med Chem. 2022 Jan 5;227:113948. |