| Bioactivity | FGFR4-IN-22 (compound 10f) is a potent inhibitor of FGFR4, with the IC50 of 5.4 nM. FGFR4-IN-22 serve as a potential lead compound targeting FGFR4 for anti-HCC agent development[1]. |
| CAS | 2922812-74-4 |
| Formula | C36H34F3N7O2 |
| Molar Mass | 653.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lei Han, et al. Design, synthesis, and biological evaluation of Ponatinib-based N-Phenylpyrimidine-2-amine derivatives as novel fibroblast growth factor receptor 4 (FGFR4) selective inhibitors. Eur J Med Chem. 2025 Feb 15:284:117206. |
FGFR4-IN-22
CAS: 2922812-74-4 F: C36H34F3N7O2 W: 653.70
FGFR4-IN-22 (compound 10f) is a potent inhibitor of FGFR4, with the IC50 of 5.4 nM. FGFR4-IN-22 serve as a potential lea
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