Bioactivity | FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1]. |
Invitro | FGFR3 (example 297) 抑制 FGFR3 活性,IC50 值小于 50 nM[1]。 |
Name | FGFR3-IN-4 |
CAS | 2833706-13-9 |
Formula | C26H24ClN7O |
Molar Mass | 485.97 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Abraham, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. WO2022187443. |