| Bioactivity | FGFR2 degrader 1 (compound 28E) is a selectively degrader of FGFR2, with the DC50 of 0.645 nM. FGFR2 plays an important role in cancer research[1]. |
| Formula | C40H39Cl2N9O6 |
| Molar Mass | 812.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zuli Hu, et al. Design, synthesis and antitumor activity of a novel FGFR2-selective degrader to overcome resistance of the FGFR2V564F gatekeeper mutation based on a pan-FGFR inhibitor. Eur J Med Chem. 2024 Sep 5:275:116612. |