| Bioactivity | FGFR1 inhibitor-9 (Compound 7) is an FGFR1 inhibitor (IC50s: 0.85 nM). FGFR1 inhibitor-9 binds to the ATP-binding pocket of FGFR1. FGFR1 inhibitor-9 has anticancer activity[1]. |
| Target | 0.85 nM (FGFR1) |
| Name | FGFR1 inhibitor-9 |
| Formula | C27H20ClNO5 |
| Molar Mass | 473.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ronnakorn Leechaisit, et al. Discovery of Novel Naphthoquinone鈥揅halcone Hybrids as Potent FGFR1 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling. ACS Omega 2023. |