| Bioactivity | FGFR1 inhibitor-8 (Compound 9) is a FGFR1 inhibitor (IC50s: 0.5 nM). FGFR1 inhibitor-8 binds to the ATP-binding pocket of FGFR1. FGFR1 inhibitor-8 has anticancer activity[1]. |
| Target | 0.5 nM (FGFR1) |
| Name | FGFR1 inhibitor-8 |
| Formula | C26H18ClNO5 |
| Molar Mass | 459.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ronnakorn Leechaisit, et al. Discovery of Novel Naphthoquinone鈥揅halcone Hybrids as Potent FGFR1 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling. ACS Omega 2023. |