FGFR-IN-7_product_DataBase

CAS: 2488764-17-4 F: C16H21ClF2N4O2 W: 374.81

FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulato

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research[1].
In Vivo	FGFR-IN-7 (compound 17) (1 mg/kg, Orally, once daily for 10 days) significantly enhances recovery of coordinated movement in the in vivo rat acute stroke model[1].
Name	FGFR-IN-7
CAS	2488764-17-4
Formula	C16H21ClF2N4O2
Molar Mass	374.81
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Sakai H, et al. Fibroblast growth factor receptor modulators employing diamines with reduced phospholipidosis-inducing potential. Bioorg Med Chem. 2020 Jul 15;28(14):115562.

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