| Bioactivity | FFN511 (hydrochloride) is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 (hydrochloride) inhibits serotonin binding to VMA T2-containing membranes with an IC50 of 1 µM. FFN511 (hydrochloride) directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices[1][2]. |
| Invitro | FFN511 (hydrochloride) (350 nM；30 min) 在培养的小鼠嗜铬细胞中以与 LDCV 一致的模式积累，并且亲脂性碱基氯喹可以消除这种积累[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> FFN511 hydrochloride 相关抗体: |
| CAS | 2596358-28-8 |
| Formula | C17H21ClN2O2 |
| Molar Mass | 320.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gubernator NG, et al. Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science. 2009 Jun 12;324(5933):1441-4. [2]. Keighron JD, et al. Analytical tools to monitor exocytosis: a focus on new fluorescent probes and methods. Analyst. 2012 Apr 21;137(8):1755-63. |
FFN511 hydrochloride
CAS: 2596358-28-8 F: C17H21ClN2O2 W: 320.81
FFN511 (hydrochloride) is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine
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