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FFA1 agonist-1

CAS: 2417231-16-2 F: C27H36ClNO3 W: 458.03

FFA1 agonist-1 (Compound 17a) is an orally active fatty acid receptor 1 (FFA1) agonist with an EC50 of 0.75 μM. FFA1 ag
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Bioactivity FFA1 agonist-1 (Compound 17a) is an orally active fatty acid receptor 1 (FFA1) agonist with an EC50 of 0.75 μM. FFA1 agonist-1 can be used for type 2 diabetes mellitus research[1].
Target EC50: 0.75 μM (FFA1)
In Vivo FFA1 agonist-1 (Compound 17a) (0-25 mg/kg; p.o.) reduces the plasma glucose levels in a dose-dependent manner in mice[1].
Name FFA1 agonist-1
CAS 2417231-16-2
Formula C27H36ClNO3
Molar Mass 458.03
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Kuranov SO, et al. Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40). Bioorg Chem. 2020 Jun;99:103830.