| Bioactivity | FAUC 365 is a highly dopamine D3 receptor-selective antagonist with Ki values of 0.5 nM, 340, 2600, and 3600 nM at D3, D4.4, D2short, and D2Long receptors, respectively. FAUC 365 can be used for the research of schizophrenia, and Parkinson's disease[1][2]. | ||||||||||||
| Name | FAUC 365 | ||||||||||||
| CAS | 474432-66-1 | ||||||||||||
| Formula | C23H25Cl2N3OS | ||||||||||||
| Molar Mass | 462.44 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Philip Seeman, et al. Dopamine D2 and D3 receptors in human putamen, caudate nucleus, and globus pallidus. Synapse. 2006 Sep 1;60(3):205-11. [2]. Carsten Hocke, et al. Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3963-6. |
FAUC 365
CAS: 474432-66-1 F: C23H25Cl2N3OS W: 462.44
FAUC 365 is a highly dopamine D3 receptor-selective antagonist with Ki values of 0.5 nM, 340, 2600, and 3600 nM at D3, D
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