| Bioactivity | FAP-IN-4 (Comp 10) is a fibroblast activation protein (FAP) inhibitor and a 18F-labeled PET tracer targeting FAP. FAP-IN-4 can be used for cancer research[1]. |
| In Vivo | FAP-IN-4 (p.i.; 5.1−7.4 MBq; 15-60 min; 单剂量) 在 CD1 nude 老鼠中显示很快的血液清除率[1]。FAP-IN-4 (p.i.; 5−7.4 MBq; 60 min; 单剂量) 在 U-87MG tumor-bearing 老鼠的 PET 成像中表现出良好的肿瘤靶向性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C30H34F3N5O6S |
| Molar Mass | 649.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Muhammet T, et al. Druglike, 18F-labeled PET Tracers Targeting Fibroblast Activation Protein. Journal of Medicinal Chemistry 2024 67 (9), 7068-7087 |