| Bioactivity | FAM49B (190-198) mouse is a peptide fragment of FAM49B. FAM49B is a mitochondria-localized protein that regulates mitochondrial fission. FAM49B regulates mitochondrial function and integrity and tumor progression. FAM49B is also a negative regulator in T cell activation, it acts by repressing GTPase Rac activity and modulating cytoskeleton reorganization[1]. |
| CAS | 1588388-60-6 |
| Sequence | Phe-Tyr-Ala-Glu-Ala-Thr-Pro-Met-Leu |
| Shortening | FYAEATPML |
| Formula | C49H71N9O14S |
| Molar Mass | 1042.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chattaragada MS, et al. FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis. Oncogene. 2018 Feb 8;37(6):697-709. |