| Bioactivity | FAK-IN-24 (Compound 9f) is a FAK inhibitor (IC50: 0.815 nM). FAK-IN-24 induces DNA damage and apoptosis. FAK-IN-24 has anti-glioblastoma activity. FAK-IN-24 inhibits proliferation of glioblastoma cell lines U87-MG (IC50 = 15 nM) and U251 (IC50 = 20 nM). FAK-IN-24 induces tumor growth in U87-MG xenograft model[1]. |
| CAS | 3062175-62-3 |
| Formula | C39H45Cl2F3N8O3 |
| Molar Mass | 801.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wei Y, et al. Discovery of noncovalent diaminopyrimidine-based Inhibitors for glioblastoma via a dual FAK/DNA targeting strategy. Eur J Med Chem. 2025 Mar 15;286:117288. |
FAK-IN-24
CAS: 3062175-62-3 F: C39H45Cl2F3N8O3 W: 801.73
FAK-IN-24 (Compound 9f) is a FAK inhibitor (IC50: 0.815 nM). FAK-IN-24 induces DNA damage and apoptosis. FAK-IN-24 has a
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.