| Bioactivity | FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase[1]. |
| Name | FAK-IN-14 |
| CAS | 2766666-22-0 |
| Formula | C21H24BrN7OS |
| Molar Mass | 502.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhiwu Long, et al. Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors. Bioorg Chem. 2023. |
FAK-IN-14
CAS: 2766666-22-0 F: C21H24BrN7OS W: 502.43
FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87
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