| Bioactivity | FABP1-IN-1 (44) is a selective FABP1 inhibitor, with an IC50 of 4.46 μM. FABP1-IN-1 (44) can be used for the research of NASH[1]. |
| Target | IC50: 4.46 μM (FABP1), >30 μM (FABP3), >15 μM (FABP4). |
| In Vivo | FABP1-IN-1 (44) 能缓解非酒精性脂肪性肝炎（NASH）小鼠的典型组织学特征，包括脂肪变性、小叶炎症、肝细胞肿胀和纤维化。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Formula | C30H25NO5 |
| Molar Mass | 479.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ya Chen, et al. Design, synthesis, and biological evaluation of first-in-class FABP1 inhibitors for the treatment of NASH. Eur J Med Chem. 2024 Apr 15:270:116358. |