| Bioactivity | F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD)[1]. |
| Target | IC50: 1.25 μM (Frizzled receptor, FZD7) |
| Name | F7H |
| CAS | 897109-93-2 |
| Formula | C24H18FN3O2S2 |
| Molar Mass | 463.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li C, et al. Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J Med Chem. 2023 Sep 14;66(17):11855-11868.. . |