F0045(S)_product_DataBase

Bioactivity	F0045(S) is a potent influenza hemagglutinin inhibitor with a KD value of 6.1 µM. F0045(S) protects human cells from influenza infection[1][2].
Invitro	F0045(S) 对 H1/Beijing、H1/Cal04 和 H5 A/Vietnam/1203/2004 感染的 MDCK-SIAT1 细胞显示中和作用，EC50 值分别为 1.6、3.9、22.8 µM[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> F0045(S) 相关抗体:
CAS	2716077-17-5
Formula	C17H15Cl2NO2
Molar Mass	336.21
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Kitamura S, et al. Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2310677121. [2]. Yao Y, et al. An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18431-18438.

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