| Bioactivity | Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). IC50 value: 220/150 nMTarget: L-glutamate uptake receptorEvans blue is a biological dye, for detection of cell survival. Evans Blue can not penetrate healthy cell membrane, but can penetrate into death cell. Binds with high affinity to serum albumin. |
| Name | Evans Blue |
| CAS | 314-13-6 |
| Formula | C34H24N6Na4O14S4 |
| Molar Mass | 960.81 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Evans Blue
CAS: 314-13-6 F: C34H24N6Na4O14S4 W: 960.81
Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT).
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