| Bioactivity | Eutypenes I (Compound 9) inhibits the secretion of VEGF-A, inhibits the activation of VEGFR and the downstream Erk/Akt signaling pathway. Eutypenes I inhibits the migration of cell HMEC-1, and exhibits anti-angiogenic activity in Sprague-Dawley’s rat models[1]. |
| Formula | C15H24O3 |
| Molar Mass | 252.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li WS, et al., Discovery of marine ent-eudesmane sesquiterpenoids as angiogenic inhibitors via suppressing VEGF-A/VEGFR2 signaling pathway. Bioorg Chem. 2025 Jan;154:108055. |