| Bioactivity | Euphornin is a anticaner agent, that can be isolated from E. helioscopia. Euphornin induces apoptosis via caspase-mediated pathways. Euphornin induces cell cycle arrest by increasing the level of the phospho-CDK1 (Tyr15) protein[1]. |
| Invitro | Euphornin (50-200 μg/mL, 48 h) 显著增加裂解的 caspase-3、caspase-8、caspase-9 和 caspase-10 的水平[1]。 |
| Name | Euphornin |
| CAS | 80454-47-3 |
| Formula | C33H44O9 |
| Molar Mass | 584.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li XQ, et al. Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest. Onco Targets Ther. 2018 Jul 27;11:4395-4405. |