| Bioactivity | Etrasimod arginine is an orally available S1P receptor modulator that is a potent full agonist of the S1P1 receptor and has partial agonist activity at S1P4. Etrasimod arginine reduces inflammation in a CD4+CD45RBhigh T cell-transferred mouse colitis model[1]. |
| Target | As a full agonist of recombinant human (6.1 nM EC50), mouse (3.65 nM EC50), dog (4.19 nM EC50), and monkey (8.7 nM EC50) S1P1 receptors As a partial agonist of human S1P4 (147 nM EC50) and S1P5 (24.4 nM EC50) |
| CAS | 1206123-97-8 |
| Formula | C32H40F3N5O5 |
| Molar Mass | 631.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Etrasimod arginine. Sphingosine-1-phosphate receptor 1 (S1P1 receptor) agonist, Treatment of ulcerative colitis |
Etrasimod arginine
CAS: 1206123-97-8 F: C32H40F3N5O5 W: 631.69
Etrasimod arginine is an orally available S1P receptor modulator that is a potent full agonist of the S1P1 receptor and
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.