Bioactivity | Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, blocks TIGIT interaction with PVR (CD155; poliovirus receptor) and inhibits downstream signalling with target cell killing[1]. |
Name | Etigilimab |
CAS | 2044984-83-8 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Meredith McKean, et al. Safety and efficacy of etigilimab in combination with nivolumab in select recurrent/advanced solid tumors. |