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Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate

CAS: 28705-46-6 F: C16H19NO4 W: 289.33

Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate is a potent and selective inhibitor of hMAO-B with an IC50 of 45.
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Bioactivity Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate is a potent and selective inhibitor of hMAO-B with an IC50 of 45.52 μM[1].
Name Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate
CAS 28705-46-6
Formula C16H19NO4
Molar Mass 289.33
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Secci D, et al. Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives. Eur J Med Chem. 2011 Oct;46(10):4846-52.