| Bioactivity | Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer[1]. |
| Invitro | Estrone O-sulfamate (Estrone 3-O-sulfamate) 在胎盘微粒体 (P.M.) 制剂和 MCF-7 细胞中对 STS 具有抑制活性，IC50 值分别为 18 nM 和 0.83 nM[1]。 |
| Name | Estrone O-sulfamate |
| CAS | 148672-09-7 |
| Formula | C18H23NO4S |
| Molar Mass | 349.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. L W Lawrence Woo, et al. Synthesis and evaluation of analogues of estrone-3-O-sulfamate as potent steroid sulfatase inhibitors. Bioorg Med Chem. 2012 Apr 15;20(8):2506-19. |
Estrone O-sulfamate
CAS: 148672-09-7 F: C18H23NO4S W: 349.44
Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhib
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