| Bioactivity | Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering[1][2]. | ||||||||||||
| Invitro | Estradiol (10 nM, 7 days) induces neural differentiation and increased neurite branching of human endometrial stem cells (hEnSCs)[1].Estradiol (17β-estradiol, 10 nM, 7 days) increases the expression of neuron-like cell markers (Tuj-1, nestin and NF-H) in neural-like cells differentiated from hEnSCs[1]. Cell Differentiation Assay[1] Cell Line: | ||||||||||||
| Name | Estradiol | ||||||||||||
| CAS | 50-28-2 | ||||||||||||
| Formula | C18H24O2 | ||||||||||||
| Molar Mass | 272.38 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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