| Bioactivity | Eritoran is a Toll-like receptor 4 (TLR4) antagonist. Eritoran protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran decreases the level of granulocytosis, may alleviate the severity of the "cytokine storm". Eritoran inhibits pathogenesis of filovirus infection[1]. |
| In Vivo | Eritoran (233 μg/小鼠；腹腔注射；10 天) 保护小鼠免受 EBOV 致死性感染，实验结束时保有 70% 的生存率[1]。 Animal Model: |
| Name | Eritoran |
| CAS | 185955-34-4 |
| Formula | C66H126N2O19P2 |
| Molar Mass | 1313.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Younan P, et al. The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge. mBio. 2017 Apr 25;8(2):e00226-17. |
Eritoran
CAS: 185955-34-4 F: C66H126N2O19P2 W: 1313.66
Eritoran is a Toll-like receptor 4 (TLR4) antagonist. Eritoran protects mice against lethal influenza virus infection, s
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.