| Bioactivity | Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocationof PKCε, but not α-, β-, and δPKC[1]. | ||||||
| Invitro | Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide containing the site for its specific receptor for activated C kinase (RACK), inhibits translocation of PKCε and reduces insulin response to glucose[1].Epsilon-V1-2 (ε-V1-2; 1 µM, 24 hours) treatment significantly inhibits Oleic acid (OA)-induced connexin 43 (Cx43) Ser368 phosphorylation and prevents OA-induced gap junction disassembly in cardiomyocytes[2]. | ||||||
| Name | Epsilon-V1-2 | ||||||
| CAS | 182683-50-7 | ||||||
| Shortening | EAVSLKPT | ||||||
| Formula | C37H65N9O13 | ||||||
| Molar Mass | 843.96 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Epsilon-V1-2
CAS: 182683-50-7 F: C37H65N9O13 W: 843.96
Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocation
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.