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Epolactaene

CAS: 167782-17-4 F: C21H27NO6 W: 389.44

Epolactaene is a potent Topoisomerase II and DNA Polymerase inhibitor with IC50 values of 10, 25, 94 µM for Topoisomera
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Epolactaene is a potent Topoisomerase II and DNA Polymerase inhibitor with IC50 values of 10, 25, 94 µM for Topoisomerase II, DNA Polymerase α, DNA Polymerase β, respectively[1].
CAS 167782-17-4
Formula C21H27NO6
Molar Mass 389.44
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Mizushina Y, et al. Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, selectively inhibits the activities of mammalian DNA polymerases and human DNA topoisomerase II. Biochem Biophys Res Commun. 2000 Jul 5;273(2):784-8.