Bioactivity | Epofolate (BMS 753493) is a folate receptor-targeted epimycin folate conjugate with antitumor activity. Epofolate overstabilizes microtubules to inhibit tumor cell mitosis, leading to cell cycle arrest and apoptosis. Epofolate can be used in the research of antitumor drug development[1]. |
CAS | 958646-17-8 |
Formula | C67H92N16O22S3 |
Molar Mass | 1569.74 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gokhale M, et al. Degradation of BMS-753493, a novel epothilone folate conjugate anticancer agent[J]. Drug development and industrial pharmacy, 2013, 39(9): 1315-1327. |