PeptideDB

Eplerenone

CAS: 107724-20-9 F: C24H30O6 W: 414.49

Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also
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Bioactivity Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV)[1][2].
Invitro Eplerenone inhibits the human mineralocorticoid receptor with IC50 value of 0.081 μM[2].
Name Eplerenone
CAS 107724-20-9
Formula C24H30O6
Molar Mass 414.49
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month