| Bioactivity | Epirizole (Mepirizole) is an orally active NSAID (nonsteroidal anti-inflammatory drug). Epirizole shows anti-inflammatory activity, and can be used in chronic rheumatoid arthritis research[1]. |
| Invitro | Epirizole (1-1000 μM; 24 h) increases MDR1 mRNA expression in Caco-2 cells[1]. RT-PCR[1] Cell Line: |
| Name | Epirizole |
| CAS | 18694-40-1 |
| Formula | C11H14N4O2 |
| Molar Mass | 234.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Takara K, et al. Effects of nonsteroidal anti-inflammatory drugs on the expression and function of P-glycoprotein/MDR1 in Caco-2 cells. Drug Chem Toxicol. 2009;32(4):332-7. |