Bioactivity | Epipregnanolone, a naturally occurring 5β-reduced neurosteroid, is a potent, voltage-dependent blocker of T-channels. Epipregnanolone inhibits DRG T-currents with an IC50 of 2 μM (at Vh of -90 mV). Epipregnanolone acts as a partial agonist on a common neurosteroid modulatory site of the GABAA receptor complex in avian CNS[1][2]. | ||||||||||||
Name | Epipregnanolone | ||||||||||||
CAS | 128-21-2 | ||||||||||||
Formula | C21H34O2 | ||||||||||||
Molar Mass | 318.49 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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