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Epipregnanolone

CAS: 128-21-2 F: C21H34O2 W: 318.49

Epipregnanolone, a naturally occurring 5β-reduced neurosteroid, is a potent, voltage-dependent blocker of T-channels.Ep
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Bioactivity Epipregnanolone, a naturally occurring 5β-reduced neurosteroid, is a potent, voltage-dependent blocker of T-channels. Epipregnanolone inhibits DRG T-currents with an IC50 of 2 μM (at Vh of -90 mV). Epipregnanolone acts as a partial agonist on a common neurosteroid modulatory site of the GABAA receptor complex in avian CNS[1][2].
Name Epipregnanolone
CAS 128-21-2
Formula C21H34O2
Molar Mass 318.49
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month